Access to biological samples in store

The Danish National Biobank stores millions of biological samples that can be used for research projects.

Many samples are from specific research project or national screenings. This means that data on the donors and screening results are often available. Further via the Danish Biobank Register, information such as donor age, gender, diagnose, operation procedures etc. can be linked to the samples

Biological samples in the Danish National Biobank
Serum 4,200,000
Dried blood spot samples 2,200,000
Plasma 1,300,000
Whole blood 560,000
DNA 510,000
Urine 310,000
Blood clot 188,000
Amniotic fluid 70,000
Saliva 70,000
Buffy Coat 60,000
Cord Blood Mononuclear Cells 60,000
Proteins from DBS 50,000
Spinal fluid 30,000
DNA from feaces 20,000
Peripheral Blood Mononuclear Cells (PBMC) 1,500
Breast Milk 600
SUM 9,630,100

As a scientist you can apply for sample retrieval from the Danish National Biobank, the process involve 4 steps:

3) The application is assessed by the DNB Scientific Board

4) Samples are handed out

1) To gain access, your project must be approved by a research ethics committee. According to Danish law, all research projects involving human biological material must obtain such an approval. Researchers from abroad who collaborate with a Danish institution responsible for data, either as part of a public research institution or an established non-commercial research and analysis environment, may gain access to material from the DNB. Likewise, Danish and foreign companies that collaborate with a Danish institution responsible for data, i.e. a research institution of an established non-commercial research and analysis environment, may gain access to material from the DNB.

 

2) Once approval is obtained, you apply through the national access system for biological samples and health data, Scientific Services at the Danish Health Data Authority. From here the application is forwarded to the Coordinating Centre at the Danish National Biobank. Besides an ethics committee approval, you must submit a project description, sample retrieval list, and a statement that the funds necessary to retrieve the samples are available. If the biological samples are located in external biobanks, the Coordinating Centre can coordinate the application, so that you as a researcher only has to apply once. The Coordinating Centre can furthermore guide and advise about access to samples.

 

3) Incoming applications are assessed by the Scientific Board. The Board is made up of: 2 persons from SSI, among these the chairman, 1 person from the Danish Council for Independent Research| Medical Sciences, 1 person from the Danish Regions, and 1 person from the organisation Danish Patients. The Scientific Board evaluates applications in the order they are received and responds no later than one month from receipt of a complete application.

 

4) Agreement of the terms for sample retrieval and handling is made by the DNB laboratory and the scientist. The normal limit is set to 100 µl serum/plasma or 1 µg DNA. Sample are retrieved and handed out.

Danmarks Nationale Biobank • Artillerivej 5 • 2300 København S • T 3268 9163 / 3268 5199 • mail@nationalbiobank.dk

1) To gain access, your project must be approved by a research ethics committee. According to Danish law, all research projects involving human biological material must obtain such an approval. Researchers from abroad who collaborate with a Danish institution responsible for data, either as part of a public research institution or an established non-commercial research and analysis environment, may gain access to material from the DNB. Likewise, Danish and foreign companies that collaborate with a Danish institution responsible for data, i.e. a research institution of an established non-commercial research and analysis environment, may gain access to material from the DNB.

2) Once approval is obtained, you apply through the national access system for biological samples and health data, Scientific Services at the Danish Health Data Authority. From here the application is forwarded to the Coordinating Centre at the Danish National Biobank. Besides an ethics committee approval, you must submit a project description, sample retrieval list, and a statement that the funds necessary to retrieve the samples are available. If the biological samples are located in external biobanks, the Coordinating Centre can coordinate the application, so that you as a researcher only has to apply once. The Coordinating Centre can furthermore guide and advise about access to samples.